The episode starts with a narrator, who says nothing in life is permanent, and that humans have always fought against death. The setting changes to the inside of Romero & Carpen Town 's police station, where Panty, Stocking, Garterbelt, and a few other humans are trying to repel a horde of zombies trying to get inside. Panty tries shooting a zombie dog, but it is unaffected. Everyone inside the station tells the angels to kill the zombies already, but Panty explains that their weapons don't work against zombies, making it impossible for them to do anything. The humans start calling the angels impostors when suddenly a policeman reveals to them that the zombies' weakness is fire.
Garterbelt explains that zombies can be defeated, but since he has diarrhea, he goes back to the bathroom before he can reveal their weakness. Meanwhile, a policeman lights a chair on fire and throws it at the zombies, but nothing happens. The zombies are able to get inside the station and soon transform many of the remaining humans into zombies. Garterbelt comes out of the bathroom once again and tells the Anarchy sisters that in order to defeat a zombie, they needed to destroy their brains. Stocking says there had to be a more elegant way of defeating them, however Panty goes ahead and smashes a zombie's head.
Panty assures them that all they really need to do is get into the weaponry shop nearby, and throws a gas container to the zombies outside, making it explode after shooting it. The remaining survivors run to the shop, but it turns out to be a sex shop . The Anarchy sisters start blaming Garterbelt for making them cops for a day. Meanwhile, from a good distance, Scanty and Kneesocks are watching the scene unfold. It is revealed that they are the ones behind the zombie incident, turning dead people into zombies just by dripping the zombie liquid they ordered from a demon catalogue on them. A zombie cat delivers the demons' message to Panty and Stocking, who become enraged and started fighting the cat.
The remaining survivors prepare themselves to battle the zombies, but one of the survivors - already bitten by the undead - says he is willing to act as a decoy in exchange for someone publishing the book of his stormy life. However, he spends too much time preparing to distract the horde, and thus turns within moments of exiting the store. As the few remaining humans fall to the relentless legion of zombies, Garterbelt orders the angels to get inside See Through, and then come pick everyone up. Panty and Stocking narrowly manage to reach their vehicle, but plan to simply ditch the others and escape the ravaged town. However, they are attacked by Chuck, who was turned into a zombie earlier.
The newly-zombified Panty and Stocking then come after Garterbelt, who is now the only remaining survivor. Panty claims that she feels liberated by the experience, but wonders if they can change back to normal; Stocking suggests that they may revert at dawn, but insists that they discuss the matter after getting fresh meat from their former caretaker. Musing that his charges' bodies are now as rotten as their minds, Garterbelt calmly pulls a second shotgun from his afro and opens fire.
Meanwhile, Scanty rejoices in victory upon seeing her foes reduced to undead. Unfortunately, her joyful jumping causes her to splash the zombie liquid all around the hill. By the time Kneesocks gets Scanty to stop, the demon sisters find themselves surrounded by ravenous ghouls, with nothing to eat but themselves...
As dawn breaks, Panty and Stocking sit atop the sex shop's roof, munching on the remains of Garterbelt. Panty notices that they haven't changed back, prompting Stocking to wonder what they should do next. As the zombified demon sisters lurch by on the street, the angels decide to sit back and relax; far away, church bells ring.